Quanchi Chen is a 4th year PhD student at the Leiden University where he uses the zebrafish embryos model to study cancer. More specifically, for his research, Quanchi makes use of a zebrafish tumor model to investigate the mechanism of tumor angiogenesis and find the suitable drugs to deplete tumor cells. The dynamics of melanoma induced angiogenesis is macrophage dependent in this model. During melanoma cell growth, macrophages are attracted to – and activated in – the tumor site. The vascular endothelial growth factor (VEGF) is an important cytokine secreted by these macrophages. The VEGF was shown to drive tumor vessel formation in the zebrafish model. With this research project, Quanchi hopes to bridge the molecular function and dynamic cell movements in a live model.
He has some experience in science communication and wishes to describe his own ideas clear and easy to a wider public. In order to do so, he believes it is of importance to keep in mind that different people have different backgrounds and thus one should be patient when communicating with different people. Quanchi joined the ScientistWanted project to tell people what he is doing and to communicate with other scientists as well.
Quanchi can be found on: